Neurobiology of substance use disorder |
The Mitra lab studies circuit, epigenetic, and post-translational modifications underlying exposure to drugs of abuse. We also examine how stress influences drug taking and relapse through long term neuroadaptations in the mesolimbic dopamine pathways. We use pharmacology, chemogenetics, viral-mediated gene transfer, and cell-type specific tools.
|
|
|
Chemogenetic circuit manipulation
Chromatin immunoprecipitation (ChIP)
|
RNAscope In-Situ Hybridization
Viral-mediated gene transfer
|