Publications

List of publications:

2026

Malabika Maulik, Claire Rose, Souradip Mallick, Audrey Jones, Anastasia Dodge, Songjukta Chakraborty, Aaliyah Carter, Ann Jeffers, Mattea Ford, Emma Zhang, Blaine Varnell, Randall Davis, Swarup Mitra (2026) Oxycodone induces HMGB1-mediated neuroimmune crosstalk between oligodendrocytes and microglia. Neuroscience. https://doi.org/10.1016/j.neuroscience.2026.02.037

2025

Chakraborty, S., Dodge, A., Hochstetler, M., Jeffers, A., Jarome, T., & Mitra, S. (2025). Post-Translational modifications and proteomic mechanisms underlying substance use disorder. Neuroscience. https://doi.org/10.1016/j.neuroscience.2025.10.040
Hochstetler, M., Dodge, A., & Mitra, S. (2025). The neurobiological and behavioral impacts of adulterants in drugs of abuse. Brain Disorders, 20, 100296. https://doi.org/10.1016/j.dscb.2025.100296‌
Hochstetler, M., Dodge, A., Chakrabotry, S., Jeffers,A., & Mitra, S. (2025) Xylazine co-administration influences the rewarding properties of heroin and withdrawal in male rats. Pharmacology Biochemistry and Behavior, doi.org/10.1016/j.pbb.2025.174052.
Looschen K, Jeffers A, Chakraborty S, Salisbury C, Dodge A, Hochstetler M, Mitra S. (2025) Adolescent stress avoidance influences cue-induced heroin seeking and chaperonin gene expression in the dorsal striatum of adult female rats. Am J Drug Alcohol Abuse. Mar 12:1-9. doi: 10.1080/00952990.2025.2469793

2024

Mitra S, Werner CT, Shwani T, Lopez AG, Federico D, Higdon K, Li X, Gobira PH, Thomas SA, Martin JA, et al. A novel role for the histone demethylase JMJD3 in mediating heroin-induced relapse-like behaviors. Biol Psychiatry. Jul;97:S602–613. doi:10.1016/j.biopsych.2024.06.028.(2024).
Looschen K, Khatri SN, Maulik M, Salisbury C, Carman AF, Corriveau K, Smith C, Manetti D, Romanelli MN, Arias HR, Gipson CD, Mitra S. Novel psychoplastogen DM506 reduces cue-induced heroin-seeking and inhibits tonic GABA currents in the Prelimbic Cortex. Neurochem Int. 2024 Sep;178:105785. doi: 10.1016/j.neuint.2024.105785.

2023

Lulek CF, Maulik M, Mitra S, Guindon J, Morgan DJ, Henderson-Redmond AN. Sex differences in acute delta-9-tetrahydrocannabinol (Δ9-THC) response and tolerance as a function of mouse strain. Psychopharmacology (Berl). Sep;240(9):1987-2003. doi: 10.1007/s00213-023-06421-8 (2023).
Maulik M, Looschen K, Smith C, Johnson K, Carman AF, Nagisetty C, Corriveau K, Salisbury C, Deschepper K, Michels M, Henderson-Redmond AN, Morgan DJ, Mitra S. Postpartum scarcity-adversity inflicts sex-specific cerebellar adaptations and reward behaviors in adolescence. Pharmacol Biochem Behav. 2023 Oct;231:173620. doi: 10.1016/j.pbb.2023.173620.
Piscura MK, Henderson-Redmond AN, Barnes RC, Mitra S, Guindon J, Morgan DJ. Mechanisms of cannabinoid tolerance. Biochem Pharmacol. 2023 Aug;214:115665. doi: 10.1016/j.bcp.2023.115665.

2022

Mitra, S., Banik, A., Saurabh, S., Maulik, M. & Khatri, S. N. Neuroimmunometabolism: A new pathological nexus underlying neurodegenerative disorders. J Neurosci, doi:10.1523/jneurosci.0998-21.2022 (2022)
Fulton, S*. L., Mitra, S*., Lepack, A. E., Martin, J. A., Stewart, A. F., Converse, J., Hochstetler, M., Dietz, D. M. & Maze, I. Histone H3 dopaminylation in ventral tegmental area underlies heroin-induced transcriptional and behavioral plasticity in male rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, doi:10.1038/s41386-022-01279-4 (2022). (*Co-first)

2021

Mitra, S., Werner, C. & Dietz, D. M. Neuroadaptations and TGF-β signaling: emerging role in models of neuropsychiatric disorders. Mol Psychiatry, doi:10.1038/s41380-021-01186-y (2021).
Mitra, S*., Gobira, P. H*., Werner, C. T., Martin, J. A., Iida, M., Thomas, S. A., Erias, K., Miracle, S., Lafargue, C., An, C. & Dietz, D. M. A role for the endocannabinoid enzymes monoacylglycerol and diacylglycerol lipases in cue-induced cocaine craving following prolonged abstinence. Addict Biol 26, e13007, doi:10.1111/adb.13007 (2021). (*Co-first)
Mitra, S. & Bult-Ito, A. Bidirectional Behavioral Selection in Mice: A Novel Pre-clinical Approach to Examining Compulsivity. Frontiers in psychiatry 12, 716619, doi:10.3389/fpsyt.2021.716619 (2021).

2020

Werner, C. T*., Mitra, S*., Auerbach, B. D., Wang, Z. J., Martin, J. A., Stewart, A. F., Gobira, P. H., Iida, M., An, C., Cobb, M. M., Caccamise, A., Salvi, R. J., Neve, R. L., Gancarz, A. M. & Dietz, D. M. Neuroadaptations in the dorsal hippocampus underlie cocaine seeking during prolonged abstinence. Proceedings of the National Academy of Sciences of the United States of America 117, 26460-26469, doi:10.1073/pnas.2006133117 (2020). (*Co-first)

Mitra, S., Santana Miranda, V., McMillan, C., Dykes, D., Mucha, M., Marth, T. E., Poe, B., Basu, D. G. & Bult-Ito, A. Trait specific modulatory effects of caffeine exposure on compulsive-like behaviors in a spontaneous mouse model of obsessive-compulsive disorder. Behav Pharmacol 31, 622-632, doi:10.1097/fbp.0000000000000570 (2020).
Mitra, S., Khatri, S. N., Maulik, M., Bult-Ito, A. & Schulte, M. Allosterism of Nicotinic Acetylcholine Receptors: Therapeutic Potential for Neuroinflammation Underlying Brain Trauma and Degenerative Disorders. Int J Mol Sci 21, doi:10.3390/ijms21144918 (2020).
Lepack, A. E., Werner, C. T., Stewart, A. F., Fulton, S. L., Zhong, P., Farrelly, L. A., Smith, A. C. W., Ramakrishnan, A., Lyu, Y., Bastle, R. M., Martin, J. A., Mitra, S., O'Connor, R. M., Wang, Z. J., Molina, H., Turecki, G., Shen, L., Yan, Z., Calipari, E. S., Dietz, D. M., Kenny, P. J. & Maze, I. Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking. Science 368, 197-201, doi:10.1126/science.aaw8806 (2020).
Engeln, M., Mitra, S., Chandra, R., Gyawali, U., Fox, M. E., Dietz, D. M. & Lobo, M. K. Sex-Specific Role for Egr3 in Nucleus Accumbens D2-Medium Spiny Neurons Following Long-Term Abstinence From Cocaine Self-administration. Biological psychiatry 87, 992-1000, doi:10.1016/j.biopsych.2019.10.019 (2020).

2019

Maulik, M*., Mitra, S*., Sweeney, M., Lu, B., Taylor, B. E. & Bult-Ito, A. Complex interaction of dietary fat and Alaskan bog blueberry supplementation influences manganese mediated neurotoxicity and behavioral impairments. J Funct Foods 53, 306-317, doi:10.1016/j.jff.2018.12.028 (2019). (*Co-first)
Maulik, M*., Mitra, S*., Basmayor, A. M., Lu, B., Taylor, B. E. & Bult-Ito, A. Genetic Silencing of Fatty Acid Desaturases Modulates α-Synuclein Toxicity and Neuronal Loss in Parkinson-Like Models of C. elegans. Front Aging Neurosci 11, 207, doi:10.3389/fnagi.2019.00207 (2019). (*Co-first)

2018

Werner, C. T., Viswanathan, R., Martin, J. A., Gobira, P. H., Mitra, S., Thomas, S. A., Wang, Z. J., Liu, J. F., Stewart, A. F., Neve, R. L., Li, J. X., Gancarz, A. M. & Dietz, D. M. E3 Ubiquitin-Protein Ligase SMURF1 in the Nucleus Accumbens Mediates Cocaine Seeking. Biological psychiatry 84, 881-892, doi:10.1016/j.biopsych.2018.07.013 (2018).
Mitra, S. & Bult-Ito, A. Attenuation of compulsive-like behavior by fluvoxamine in a non-induced mouse model of obsessive-compulsive disorder. Behav Pharmacol 29, 299-305, doi:10.1097/fbp.0000000000000348 (2018).
Maulik, M., Mitra, S., Hunter, S., Hunstiger, M., Oliver, S. R., Bult-Ito, A. & Taylor, B. E. Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans. Sci Rep 8, 10216, doi:10.1038/s41598-018-26905-4 (2018).

2017

Mitra, S., Mucha, M., Owen, S. & Bult-Ito, A. Postpartum Lactation-Mediated Behavioral Outcomes and Drug Responses in a Spontaneous Mouse Model of Obsessive-Compulsive Disorder. ACS Chem Neurosci 8, 2683-2697, doi:10.1021/acschemneuro.7b00231 (2017).
Mitra, S., Bastos, C. P., Chesworth, S., Frye, C. & Bult-Ito, A. Strain and sex based characterization of behavioral expressions in non-induced compulsive-like mice. Physiol Behav 168, 103-111, doi:10.1016/j.physbeh.2016.11.002 (2017).
Maulik, M., Mitra, S., Bult-Ito, A., Taylor, B. E. & Vayndorf, E. M. Behavioral Phenotyping and Pathological Indicators of Parkinson's Disease in C. elegans Models. Front Genet 8, 77, doi:10.3389/fgene.2017.00077 (2017).

2016

Mitra, S., Mucha, M., Khatri, S. N., Glenon, R., Schulte, M. K. & Bult-Ito, A. Attenuation of Compulsive-Like Behavior Through Positive Allosteric Modulation of α4β2 Nicotinic Acetylcholine Receptors in Non-Induced Compulsive-Like Mice. Front Behav Neurosci 10, 244, doi:10.3389/fnbeh.2016.00244 (2016).
Mitra, S., Mucha, M., Khatri, S. N., Glenon, R., Schulte, M. K. & Bult-Ito, A. Attenuation of Compulsive-Like Behavior Through Positive Allosteric Modulation of α4β2 Nicotinic Acetylcholine Receptors in Non-Induced Compulsive-Like Mice. Front Behav Neurosci 10, 244, doi:10.3389/fnbeh.2016.00244 (2016).
Mitra, S., Bastos, C. P., Bates, K., Pereira, G. S. & Bult-Ito, A. Ovarian Sex Hormones Modulate Compulsive, Affective and Cognitive Functions in A Non-Induced Mouse Model of Obsessive-Compulsive Disorder. Front Behav Neurosci 10, 215, doi:10.3389/fnbeh.2016.00215 (2016).